Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEKP5HX)

DME Name	Cholesterol 24-hydroxylase (CYP46A1) DME Info
Gene Name	CYP46A1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dextromethorphan	DMUDJZM	Allergic rhinitis	CA08.0	Approved	[1]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[1]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[1]
Testosterone cypionate	DMC1TEV	N. A.	N. A.	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ANW-32821	DMMJOZD	N. A.	N. A.	Phase 2	[2]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Phenacetin	DMRQAM0	Analgesia	MB40.8	Withdrawn from market	[1]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain. Biochemistry. 2003 Dec 9;42(48):14284-92.
2	Cholesterol-metabolizing cytochromes P450. Drug Metab Dispos. 2006 Apr;34(4):513-20.