Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTG3T6X)

• DTP Name: Glucose transporter type 1, erythrocyte/brain (SLC2A1) DTP Info
• Gene Name: GLUT1

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-deoxyglucose	DMIAHVU	Solid tumour/cancer	2A00-2F9Z	Approved	[1]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[2]

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenite	DMBCO4Q	Discovery agent	N.A.	Investigative	[3]
D-glucose	DMMG2TO	Discovery agent	N.A.	Investigative	[4]
dehydroascorbic acid	DMKYQO4	Discovery agent	N.A.	Investigative	[5]

References

• [1] Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding. J Biol Chem. 1994 Aug 12;269(32):20533-8.
• [2] Oral Bioavailability and Disposition of Phytochemicals
• [3] Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid. Biochem Biophys Res Commun. 2006 Dec 15;351(2):424-30.
• [4] The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):121-38.
• [5] Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J Biol Chem. 1997 Jul 25;272(30):18982-9.