Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTJF3DX)

• DTP Name: L-type amino acid transporter 2 (SLC7A8) DTP Info
• Gene Name: LAT2

Molecule-Related Drug & Molecule List

6 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glycine	DMIOZ29	Allergic rhinitis	CA08.0	Approved	[1]
L-Alanine	DMZDN4W	Dietary shortage	5B5K	Approved	[1]
L-Phenylalanine	DMQXI9F	Malnutrition	5B50-5B71	Approved	[2]
L-Proline	DMKSTWR	Malnutrition	5B50-5B71	Approved	[1]
L-Tryptophan	DMIBH7M	Depression	6A70-6A7Z	Approved	[1]
L-Tyrosine	DM9O8DT	Malnutrition	5B50-5B71	Approved	[1]

References

• [1] The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.3.8.20)
• [2] Quantifying the relative contributions of different solute carriers to aggregate substrate transport. Sci Rep. 2017 Jan 16;7:40628.