Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT05DLS)

• DTT Name: E3 ubiquitin-protein ligase COP1 (RFWD2) DTT Info
• Gene Name: RFWD2

Molecule-Related Drug & Molecule List

5 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Flecainide	DMSQDLE	Tachyarrhythmias	BC71	Approved	[1]
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[1]
Propafenone	DMPIBJK	Tachyarrhythmias	BC71	Approved	[1]
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[1]
Tocainide	DMYNMDP	Ventricular arrhythmias	BC71	Approved	[1]

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Barucainide	DMTMS3L	Heart arrhythmia	BC65	Terminated	[2]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [2] Barucainide, a novel class Ib antiarrhythmic agent with a slow kinetic property: electrophysiologic observations in isolated canine and rabbit cardiac muscle. Am Heart J. 1990 May;119(5):1050-60.