Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT31N4S)

DTT Name	Pyruvate kinase PKLR (PKLR) DTT Info
Gene Name	PKLR

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mitapivat	DMXI8X0	Hereditary haemolytic anemia	3A10.3	Approved	[1]
Olipudase alfa	DMO8N8N	Gaucher disease	5C56.0Y	Approved	[2]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RP-L301	DMDEDV3	Pyruvate kinase deficiency	5C53.00	Phase 1	[3]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 216196.
2	FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761261
3	ClinicalTrials.gov (NCT04105166) Gene Therapy for Pyruvate Kinase Deficiency (PKD): A Phase I Clinical Trial to Evaluate the Safety of the Infusion of Autologous CD34+ Cells Transduced With a Lentiviral Vector Carrying the Codon Optimized Red Cell Pyruvate Kinase (coRPK) Gene in Adult and Pediatric Subjects With PKD. U.S.National Institutes of Health.