Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT3UY29)

DTT Name	HUMAN dihydroorotate dehydrogenase (DHODH) DTT Info
Gene Name	DHODH

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[1]
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1 Drugs in Phase 2 Trial Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IMU-838	DM5UJ9P	Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2/3 Trial	[2]
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1 Preclinical Drugs Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FA-613	DMTHLB8	Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[3]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	On dihydroorotate dehydrogenases and their inhibitors and uses. J Med Chem. 2013 Apr 25;56(8):3148-67. doi: 10.1021/jm301848w.
2	IMU-838 Targeting DHODH
3	Broad-spectrum inhibition of common respiratory RNA viruses by a pyrimidine synthesis inhibitor with involvement of the host antiviral response. J Gen Virol. 2017 May;98(5):946-954.