Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5CISB)

DTT Name	Cation channel sperm-associated protein 1 (CatSper1) DTT Info
Gene Name	CATSPER1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
HC-056456	DMOG1Q4	Discovery agent	N.A.	Investigative	[1]
NNC55-0396	DMID3F7	Discovery agent	N.A.	Investigative	[2]
PGF1alpha	DMUPWQT	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Pharmacological targeting of native CatSper channels reveals a required role in maintenance of sperm hyperactivation. PLoS One. 2009 Aug 31;4(8):e6844.
2	The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm. Nature. 2011 Mar 17;471(7338):382-6.
3	Progesterone activates the principal Ca2+ channel of human sperm. Nature. 2011 Mar 17;471(7338):387-91.