Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5U914)

DTT Name	Endothelin-converting enzyme 2 (ECE2) DTT Info
Gene Name	ECE2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CGS 35066	DMCHT27	Discovery agent	N.A.	Investigative	[1]
S136492	DMN6HE3	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

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References

1	The therapeutic potential of endothelin-1 receptor antagonists and endothelin-converting enzyme inhibitors on the cardiovascular system. Expert Opin Investig Drugs. 2002 Nov;11(11):1537-52.
2	Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2. J Med Chem. 2008 Jun 26;51(12):3378-87.