Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT84OS6)

• DTT Name: Dual-specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) DTT Info
• Gene Name: DYRK2

Molecule-Related Drug & Molecule List

5 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Harmine	DMPA5WD	Discovery agent	N.A.	Patented	[1]
PMID28766366-Compound-Scheme14BINDY	DMBQ0RN	N. A.	N. A.	Patented	[1]
PMID28766366-Compound-Scheme16DMAT	DMQ5UEA	N. A.	N. A.	Patented	[1]
PMID28766366-Compound-Scheme21Left	DMWTRUK	N. A.	N. A.	Patented	[1]
PMID28766366-Compound-Scheme21Right	DMF3X40	N. A.	N. A.	Patented	[1]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
leucettine L41	DMBYND6	Discovery agent	N.A.	Investigative	[2]

References

• [1] Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Expert Opin Ther Pat. 2017 Nov;27(11):1183-1199.
• [2] Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. J Med Chem. 2011 Jun 23;54(12):4172-86.