Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9721Y)

DTT Name	Interleukin 2 receptor beta (IL2RB) DTT Info
Gene Name	IL2RB

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NKTR 214	DM376WT	Melanoma	2C30	Phase 3	[1]
NKTR-214	DMACYW6	Melanoma	2C30	Phase 3	[2]
AFTVac	DMD3XMG	Glioblastoma multiforme	2A00.0	Phase 2	[3]
Leukocyte interleukin	DM2B0TJ	Head and neck cancer	2D42	Phase 1	[4]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DAB-486-IL-2	DM54T8J	Discovery agent	N.A.	Investigative	[5]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy. Nat Commun. 2020 Jan 31;11(1):661.
3	Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma. Clin Cancer Res. 2004 Mar 1;10(5):1574-9.
4	Leukocyte Interleukin, Inj. (LI) augmentation of natural killer cells and cytolytic T-lymphocytes. Immunopharmacol Immunotoxicol. 1995 May;17(2):247-64.
5	Interleukin 2 receptor targeted fusion toxin (DAB486-IL-2) treatment blocks diabetogenic autoimmunity in non-obese diabetic mice. Eur J Immunol. 1992 Mar;22(3):697-702.