Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9HLZ0)

DTT Name	Glutamate receptor AMPA 2 (GRIA2) DTT Info
Gene Name	GRIA2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
E-2007	DMJDYNQ	Diabetic neuropathy	8C0Z	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Paliroden	DMX8ZAQ	Parkinson disease	8A00.0	Phase 2	[2]
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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(S)-5-fluorowillardiine	DMCIZ7P	Discovery agent	N.A.	Investigative	[3]
ATPO	DMXLS78	Discovery agent	N.A.	Investigative	[3]
[3H]AMPA	DMLF7SG	N. A.	N. A.	Investigative	[3]
[3H]CNQX	DMIFKUX	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
2	Mechanism of inhibition of the GluA2 AMPA receptor channel opening by talampanel and its enantiomer: the stereochemistry of the 4-methyl group on the diazepine ring of 2,3-benzodiazepine derivatives.ACS Chem Neurosci.2013 Apr 17;4(4):635-44.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 445).