Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTBQ3OC)

DTT Name	Macrophage-stimulating protein receptor (RON) DTT Info
Gene Name	MST1R

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MK-2461	DM21WBH	Alzheimer disease	8A20	Phase 1/2	[1]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABC-7	DM2AIE9	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
Anti-RON receptor mabs	DMXACM2	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
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Molecule Interaction Atlas

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References

1	MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. Cancer Res. 2010 Feb 15;70(4):1524-33.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1816).