Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTDU0HP)

• DTT Name: Bacterial Cystathionine gamma-synthase (Bact metB) DTT Info
• Gene Name: Bact metB

Molecule-Related Drug & Molecule List

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GW-3333	DM3PMAZ	Chronic obstructive pulmonary disease	CA22	Preclinical	[1]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
N'-Pyridoxyl-Lysine-5'-Monophosphate	DM3ZHBO	Discovery agent	N.A.	Investigative	[2]

References

• [1] Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. J Mol Biol. 2001 Aug 24;311(4):789-801.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.