Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTEF5MJ)

DTT Name	ATP-binding cassette transporter C9 (ABCC9) DTT Info
Gene Name	ABCC9

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Approved Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glimepiride	DM5FSJA	Diabetic complication	5A2Y	Approved	[1]
Nicorandil	DMIYJFV	Angina pectoris	BA40	Approved	[2]
Repaglinide	DM5SXUV	Diabetic complication	5A2Y	Approved	[3]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[4]
------------------------------------------------------------------------------------

4 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BTS-67582	DM54K2P	Diabetic complication	5A2Y	Discontinued in Phase 2	[5]
KRN-2391	DMZ1SEW	Angina pectoris	BA40	Discontinued in Phase 2	[6]
BMS-191095	DMKFXTD	Angina pectoris	BA40	Discontinued in Phase 1	[7]
CCX915	DMHMST3	Multiple sclerosis	8A40	Discontinued in Phase 1	[8]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Mechanism of disopyramide-induced hypoglycaemia in a patient with Type 2 diabetes. Diabet Med. 2009 Jan;26(1):76-8.
2	A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) chann... J Mol Cell Cardiol. 2005 Jul;39(1):1-6.
3	Metformin/Repaglinide (PrandiMet) for type 2 diabetes. Med Lett Drugs Ther. 2009 Jun 1;51(1313):41-3.
4	Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. J Clin Invest. 2009 Jan;119(1):80-90.
5	BTS-67582 (Knoll Pharmaceuticals Co). IDrugs. 1999 Apr;2(4):355-9.
6	Effects of KRN2391 on ionic currents in rabbit femoral arterial myocytes
7	The mitochondrial K(ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats.J Cereb Blood Flow Metab.2007 Feb;27(2):348-55.
8	Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides. J Physiol. 2003 Feb 15;547(Pt 1):159-68.