Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTFNJ4R)

• DTT Name: Embryonic ectoderm development protein (EED) DTT Info
• Gene Name: EED

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MAK683	DMFK5IX	Diffuse large B-cell lymphoma	2A81	Phase 1/2	[1]
ORIC-944	DM0L8R9	Prostate cancer	2C82.0	Phase 1	[2]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A-395	DMSTZ14	Discovery agent	N.A.	Investigative	[3]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] Clinical pipeline report, company report or official report of ORIC Pharmaceuticals
• [3] The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017 Apr;13(4):389-395.