General Information of DTT (ID: TTFYL58)

DTT Name CaM-kinase II (CAMK2) DTT Info
Gene Name CAMK2A

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rimacalib DMSC7TN Rheumatoid arthritis FA20 Phase 2 [1]
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4 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABIO 09-01 DM0LUOM Anxiety disorder 6B00-6B0Z Investigative [2]
KN-93 DMPTMKH Discovery agent N.A. Investigative [3]
PMID18334293C15b DM1I6AY Discovery agent N.A. Investigative [4]
PMID18337095C27 DMEOHLV Discovery agent N.A. Investigative [5]
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Molecule Interaction Atlas

References

1 Role for CaMKII inhibition in rheumatoid arthritis: effects on HIF-1-induced VEGF production by rheumatoid synovial fibroblasts. Ann N Y Acad Sci. 2009 Sep;1173:706-11.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1558).
3 Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound. J Med Chem. 2002 Jan 31;45(3):563-6.
4 Pyrimidine-based inhibitors of CaMKIIdelta. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2404-8.
5 Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 3: Importance of the indole orientation. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2399-403.