Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTHDSE2)

• DTT Name: Bacterial Fumarate reductase flavoprotein (Bact frdA) DTT Info
• Gene Name: Bact frdA

Molecule-Related Drug & Molecule List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Morantel tartrate	DM560Y3	Mature gastrointestinal nematode infection	1F6Y	Approved	[1]
Oxantel pamoate	DMZ30JT	Trichuris trichiura infection	1F6G	Approved	[1]
Thiabendazole	DM7YCK3	Ascariasis	1F62	Approved	[1]

8 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2,3-DIMETHYL-1,4-NAPHTHOQUINONE	DMGXVBA	Discovery agent	N.A.	Investigative	[2]
2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE	DMJ3ATL	Discovery agent	N.A.	Investigative	[2]
2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL	DMUZDSC	Discovery agent	N.A.	Investigative	[2]
Citraconic acid	DMCIM9A	Discovery agent	N.A.	Investigative	[3]
Flavin-Adenine Dinucleotide	DM5S4GK	Discovery agent	N.A.	Investigative	[4]
Fumarate	DM9VLS2	Discovery agent	N.A.	Investigative	[4]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[2]
Malate Like Intermediate	DM4OQWZ	Discovery agent	N.A.	Investigative	[3]

References

• [1] Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87.
• [2] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [3] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
• [4] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.