Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJ21A9)

DTT Name	Cyclin-dependent kinase 12 (CDK12) DTT Info
Gene Name	CDK12

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK3186899	DMJAVN7	Leishmaniasis	1F54	Phase 1	[1]
------------------------------------------------------------------------------------

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
THZ531	DMBZ2MF	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Clinical pipeline report, company report or official report of GlaxoSmithKline.
2	Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol. 2016 Oct;12(10):876-84.