Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQF4TK)

DTT Name	Hydroxymethylglutaryl-CoA synthase 1 (HMGCS1) DTT Info
Gene Name	HMGCS1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(S)-3-hydroxy-3-methylglutaryl-CoA	DM3TW9V	Discovery agent	N.A.	Investigative	[1]
L-659,699	DMDF0KZ	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

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References

1	A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase. Anal Biochem. 2010 Jan 1;396(1):96-102.
2	Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis by beta-lactone inhibitors and binding of these inhibitors to the enzyme. Biochem J. 1993 Feb 1;289 ( Pt 3):889-95.