Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTR7L5Y)

• DTT Name: Bromodomain-containing protein 9 (BRD9) DTT Info
• Gene Name: BRD9

Molecule-Related Drug & Molecule List

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BI 7273	DMI3ANC	Acute myeloid leukaemia	2A60	Investigative	[1]
I-BRD9	DM9C8FP	Discovery agent	N.A.	Investigative	[2]
LP99	DMTZYQ3	Discovery agent	N.A.	Investigative	[3]

References

• [1] Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem. 2016 May 26;59(10):4462-75.
• [2] Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. J Med Chem. 2016 Feb 25;59(4):1425-39.
• [3] LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Angew Chem Int Ed Engl. 2015 May 18;54(21):6217-21.