Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTRBT3W)

• DTT Name: Short transient receptor potential channel 6 (TRPC6) DTT Info
• Gene Name: TRPC6

Molecule-Related Drug & Molecule List

11 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-APB	DM9AKVR	Discovery agent	N.A.	Investigative	[1]
20-HETE	DM5BAJ9	Discovery agent	N.A.	Investigative	[1]
ACAA	DMACYPW	Discovery agent	N.A.	Investigative	[1]
flufenamate	DMN8AP0	Discovery agent	N.A.	Investigative	[1]
hyp 9	DM0U8IV	Discovery agent	N.A.	Investigative	[2]
KB-R7943	DMMD5W3	Discovery agent	N.A.	Investigative	[1]
lysophosphatidylcholine	DMOGFVH	Discovery agent	N.A.	Investigative	[1]
ML9	DMP13VE	Discovery agent	N.A.	Investigative	[1]
OAG	DMOP8IJ	Discovery agent	N.A.	Investigative	[3]
SAG	DMHOG7W	Discovery agent	N.A.	Investigative	[3]
SLG	DMEBPCO	Discovery agent	N.A.	Investigative	[3]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491).
• [2] Simple 2,4-diacylphloroglucinols as classic transient receptor potential-6 activators--identification of a novel pharmacophore. Mol Pharmacol. 2010 Mar;77(3):368-77.
• [3] Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63.