Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTTPCNU)

DTT Name	G-protein coupled receptor 39 (GPR39) DTT Info
Gene Name	GPR39

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GPCR39 pepducins	DM1W5G9	Diabetic complication	5A2Y	Investigative	[1]
PMID24900608C1	DMCL6H3	Discovery agent	N.A.	Investigative	[2]
PMID25313322C15	DMDO9AJ	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 105).
2	Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example. ACS Med Chem Lett. 2013 Sep 16;4(11):1079-84.
3	Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists. ACS Med Chem Lett. 2014 Aug 4;5(10):1114-8.