Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTTPU1G)

DTT Name	Apoptosis inhibitor survivin (BIRC5) DTT Info
Gene Name	BIRC5

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 23722	DMQZI7K	Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]
SurVaxM	DMAIGTE	Glioblastoma of brain	2A00.00	Phase 2	[2]
CV-9201	DMCPZYT	Non-small-cell lung cancer	2C25.Y	Phase 1/2	[3]
EZN-3042	DMXFY18	Solid tumour/cancer	2A00-2F9Z	Phase 1	[4]
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Molecule Interaction Atlas

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References

1	Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression.Eur J Cancer.2012 Mar;48(5):763-71.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	National Cancer Institute Drug Dictionary (drug id 648549).
4	SPC3042: a proapoptotic survivin inhibitor.Mol Cancer Ther.2008 Sep;7(9):2736-45.