Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTTSGRH)

DTT Name	Leucine-rich repeat-containing GPCR 5 (LGR5) DTT Info
Gene Name	LGR5

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Preclinical Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BNC-101	DMSBM6A	Metastatic colorectal cancer	2B91	Phase 1	[1]
MCLA-158	DMF0O3X	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
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1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BNC-102	DMM1O0P	Solid tumour/cancer	2A00-2F9Z	Preclinical	[3]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
KM-4056	DMK17GN	Solid tumour/cancer	2A00-2F9Z	Investigative	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Clinical pipeline report, company report or official report of Bionomics.
2	Clinical pipeline report, company report or official report of Merus.
3	Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep 1;16(9):661.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 148).