Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTUI5H7)

DTT Name	Angiotensin-converting enzyme 2 (ACE2) DTT Info
Gene Name	ACE2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK2586881	DMU5EVR	Acute lung injury	NB32.3	Phase 2	[1]
ORE-1001	DM471ZH	Diabetic complication	5A2Y	Phase 1/2	[2]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID18324760C28	DMCTFWE	Discovery agent	N.A.	Investigative	[3]
XNT	DMPOGXU	Discovery agent	N.A.	Investigative	[4]
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Molecule Interaction Atlas

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References

1	New Developments in the Pharmacological Treatment of Hypertension: Dead-End or a Glimmer at the Horizon . Curr Hypertens Rep. 2015; 17(6): 42.
2	Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in mice. Inflamm Res. 2009 Nov;58(11):819-27.
3	Development of potent and selective phosphinic peptide inhibitors of angiotensin-converting enzyme 2. J Med Chem. 2008 Apr 10;51(7):2216-26.
4	Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension. 2008 May;51(5):1312-7.