Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTV3NH6)

• DTT Name: Calmodulin (CALM) DTT Info
• Gene Name: CALM

Molecule-Related Drug & Molecule List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aprindine	DMBXWU8	Cardiac arrhythmias	BC9Z	Approved	[1]
Halofantrine	DMOMK1V	Malaria	1F40-1F45	Approved	[2]
Trifluoperazine	DMKBYWI	Anxiety		Approved	[3]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[4]
2-Methyl-2-Propanol	DMHM5GJ	Discovery agent	N.A.	Investigative	[4]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[4]
Cacodylate Ion	DMK4XLD	Discovery agent	N.A.	Investigative	[4]
Calmidazolium	DM5ZTJL	Huntington disease	8A01.10	Investigative	[5]
MYRISTIC ACID	DMYX0BL	Discovery agent	N.A.	Investigative	[6]
N-Trimethyllysine	DMZQXLS	Discovery agent	N.A.	Investigative	[4]

References

• [1] Aprindine inhibits calmodulin-stimulated phosphodiesterase and Ca-ATPase activities. J Cardiovasc Pharmacol. 1983 Jan-Feb;5(1):151-6.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [3] Inhibitory effect of jujuboside A on glutamate-mediated excitatory signal pathway in hippocampus. Planta Med. 2003 Aug;69(8):692-5.
• [4] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [5] Calmidazolium evokes high calcium fluctuations in Plasmodium falciparum. Cell Signal. 2016 Mar;28(3):125-135.
• [6] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.