Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWNFC2)

DTT Name	Soluble guanylyl cyclase (GUCY2D) DTT Info
Gene Name	GUCY2D

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Riociguat	DMXBLMP	Chronic thromboembolic pulmonary hypertension		Approved	[1]
Vericiguat	DM7MDBE	Heart failure	BD10-BD13	Approved	[2]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FK-409	DMKVXYS	Angina pectoris	BA40	Phase 2	[3]
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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BAY412272	DM0M59T	Discovery agent	N.A.	Investigative	[4]
NS 2028	DML0N7D	Discovery agent	N.A.	Investigative	[5]
ODQ	DMSAJO8	Discovery agent	N.A.	Investigative	[6]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2021
3	Vasorelaxant mechanism of the new vasodilator, FK409. Eur J Pharmacol. 1993 Aug 15;246(3):205-12.
4	NO-independent regulatory site on soluble guanylate cyclase. Nature. 2001 Mar 8;410(6825):212-5.
5	Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase. Br J Pharmacol. 1998 Jan;123(2):299-309.
6	Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol Pharmacol. 1995 Aug;48(2):184-8.