Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYMGWX)

DTT Name	PDK-1 messenger RNA (PDK-1 mRNA) DTT Info
Gene Name	PDPK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

26 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one	DM27WDP	Discovery agent	N.A.	Investigative	[1]
BX-201	DMGK7U5	Discovery agent	N.A.	Investigative	[1]
BX-517	DMBQIEF	Discovery agent	N.A.	Investigative	[1]
ISIS 29219	DM37R5F	Discovery agent	N.A.	Investigative	[2]
ISIS 29223	DMMQPFE	Discovery agent	N.A.	Investigative	[2]
ISIS 29224	DM9UNWE	Discovery agent	N.A.	Investigative	[2]
ISIS 29232	DMLES7J	Discovery agent	N.A.	Investigative	[2]
ISIS 29233	DMGV4O7	Discovery agent	N.A.	Investigative	[2]
ISIS 29234	DM1XAPO	Discovery agent	N.A.	Investigative	[2]
ISIS 29236	DMAXD7P	Discovery agent	N.A.	Investigative	[2]
ISIS 29237	DMPYJEB	Discovery agent	N.A.	Investigative	[2]
ISIS 29239	DMHQF1J	Discovery agent	N.A.	Investigative	[2]
ISIS 29243	DMZ7UM2	Discovery agent	N.A.	Investigative	[2]
ISIS 29244	DMTHVEL	Discovery agent	N.A.	Investigative	[2]
ISIS 29246	DM0DG1K	Discovery agent	N.A.	Investigative	[2]
ISIS 29255	DMK2QPU	Discovery agent	N.A.	Investigative	[2]
ISIS 29256	DMF1MJ2	Discovery agent	N.A.	Investigative	[2]
ISIS 29257	DMUM2H1	Discovery agent	N.A.	Investigative	[2]
ISIS 29469	DMVCFQ5	Discovery agent	N.A.	Investigative	[2]
ISIS 29470	DMPCK7Y	Discovery agent	N.A.	Investigative	[2]
ISIS 29471	DMG4RMZ	Discovery agent	N.A.	Investigative	[2]
ISIS 29475	DMEBQUN	Discovery agent	N.A.	Investigative	[2]
ISIS 29477	DMKQMXV	Discovery agent	N.A.	Investigative	[2]
MiR-375	DM4P9LJ	Discovery agent	N.A.	Investigative	[3]
NU-6102	DMMOFKD	Discovery agent	N.A.	Investigative	[4]
SU-6689	DMDNA23	Discovery agent	N.A.	Investigative	[1]
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⏷ Show the Full List of 26 Investigative Drug(s)

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8.
2	US patent application no. 6,124,272, Antisense modulation of PDK-1 expression.
3	miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes. 2008 Oct;57(10):2708-17.
4	Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1353-7.