Drug General Information
Drug ID
D00BUR
Former ID
DCL000276
Drug Name
ICA-17043
Synonyms
Senicapoc; ICA 17043; Senicapoc (USAN); Bis(4-fluorophenyl)phenylacetamide; 2,2-bis(4-fluorophenyl)-2-phenylacetamide; 4-Fluoro-alpha-(4-fluorophenyl)-alpha-phenylbenzeneacetamide
Drug Type
Small molecular drug
Indication Hematopoietic [ICD10:D50-D89] Discontinued in Phase 2 [539476], [547148]
Company
Icagen
Formula
C20H15F2NO
InChI
InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24)
InChIKey
SCTZUZTYRMOMKT-UHFFFAOYSA-N
CAS Number
CAS 289656-45-7
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) KCa3.1 Target Info Modulator
References
Ref 539476(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2331).
Ref 547148Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013404)