Drug General Information
Drug ID
D00GUE
Former ID
DNC010282
Drug Name
2-(2-benzhydryl-4-phenylthiazol-5-yl)acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530588]
Formula
C24H19NO2S
Canonical SMILES
C1=CC=C(C=C1)C2=C(SC(=N2)C(C3=CC=CC=C3)C4=CC=CC=C4)CC(=<br />O)O
InChI
1S/C24H19NO2S/c26-21(27)16-20-23(19-14-8-3-9-15-19)25-24(28-20)22(17-10-4-1-5-11-17)18-12-6-2-7-13-18/h1-15,22H,16H2,(H,26,27)
InChIKey
GSFLUFCQJVKCFD-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Inhibitor [530588]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530588Bioorg Med Chem Lett. 2010 Feb 1;20(3):1181-5. Epub 2009 Dec 6.Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.
Ref 530588Bioorg Med Chem Lett. 2010 Feb 1;20(3):1181-5. Epub 2009 Dec 6.Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.