Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00LWG
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| Former ID |
DNC010597
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| Drug Name |
[Sar1,Tdf8]AngII
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| Indication | Discovery agent | Investigative | [530710] | ||
| Formula |
C51H70F3N15O10
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| Canonical SMILES |
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=C<br />(C=C3)C4(N=N4)C(F)(F)F)C(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)N<br />C(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC
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| InChI |
1S/C51H70F3N15O10/c1-6-28(4)41(66-43(73)35(21-30-13-17-33(70)18-14-30)62-45(75)40(27(2)3)65-42(72)34(61-39(71)25-57-5)9-7-19-59-49(55)56)46(76)63-36(23-32-24-58-26-60-32)47(77)69-20-8-10-38(69)44(74)64-37(48(78)79)22-29-11-15-31(16-12-29)50(67-68-50)51(52,53)54/h11-18,24,26-28,34-38,40-41,57,70H,6-10,19-23,25H2,1-5H3,(H,58,60)(H,61,71)(H,62,75)(H,63,76)(H,64,74)(H,65,72)(H,66,73)(H,78,79)(H4,55,56,59)/t28-,34-,35-,36-,37-,38-,40-,41-/m0/s1
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| InChIKey |
KSJIPXWEUUGTIY-LNEAKYCGSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Type-1 angiotensin II receptor | Target Info | Inhibitor | [530710] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| Arf6 signaling events | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| Muscle/Heart Contraction | |||||
| References | |||||