Drug General Information
Drug ID
D01HKZ
Former ID
DIB004927
Drug Name
TSR-011
Indication Non-small cell lung cancer [ICD10:C33-C34] Phase 1/2 [524619]
Company
Tesaro
Target and Pathway
Target(s) ALK tyrosine kinase receptor Target Info Inhibitor [532061], [550510]
KEGG Pathway Non-small cell lung cancer
WikiPathways Differentiation Pathway
References
Ref 524619ClinicalTrials.gov (NCT02048488) A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas. U.S. National Institutes ofHealth.
Ref 532061Treatment of ALK-positive non-small cell lung cancer. Arch Pathol Lab Med. 2012 Oct;136(10):1201-4.
Ref 550510National Cancer Institute Drug Dictionary (drug id 757983).