Drug Information

Drug General Information
Drug ID
D01PIU
Former ID
DNC004156
Drug Name
5-Chloro-3-ethyl-1-(4-fluoro-phenyl)-1H-indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526620]
Formula
C16H13ClFN
Canonical SMILES
CCC1=CN(C2=C1C=C(C=C2)Cl)C3=CC=C(C=C3)F
InChI
1S/C16H13ClFN/c1-2-11-10-19(14-6-4-13(18)5-7-14)16-8-3-12(17)9-15(11)16/h3-10H,2H2,1H3
InChIKey
APVXBLPJSJGGAJ-UHFFFAOYSA-N
PubChem Compound ID
44297094
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily H member 2 Target Info Inhibitor [526620]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium Channels
References
Ref 526620Bioorg Med Chem Lett. 2003 May 19;13(10):1829-35.Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.
Ref 526620Bioorg Med Chem Lett. 2003 May 19;13(10):1829-35.Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.