Drug Information

Drug General Information
Drug ID
D03HFM
Former ID
DNC009439
Drug Name
(1R,2R)-N-Arachidonoylcyclopropanolamide
Synonyms
Rac-trans N-arachidonoylcyclopropanolamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530070]
Formula
C23H37NO2
Canonical SMILES
CCCCCC=CCC=CCC=CCC=CCCCC(=O)NC1CC1O
InChI
1S/C23H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)24-21-20-22(21)25/h6-7,9-10,12-13,15-16,21-22,25H,2-5,8,11,14,17-20H2,1H3,(H,24,26)/b7-6-,10-9-,13-12-,16-15-/t21-,22-/m1/s1
InChIKey
LZHCSJBKBARIFQ-OXAAUTCPSA-N
PubChem Compound ID
42617984
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [530070]
Cannabinoid receptor 2 Target Info Inhibitor [530070]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 530070J Med Chem. 2009 May 14;52(9):3001-9.Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Ref 530070J Med Chem. 2009 May 14;52(9):3001-9.Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.