Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04PPP
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| Former ID |
DNC006047
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| Drug Name |
MCL-139
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [527951] | ||
| Formula |
C46H60N2O4
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| Canonical SMILES |
C1CCC23CCN(C(C2C1)CC4=C3C=C(C=C4)OC(=O)CCC(=O)OC5=CC6=C<br />(CC7C8C6(CCCC8)CCN7CC9CCC9)C=C5)CC1CCC1
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| InChI |
1S/C46H60N2O4/c49-43(51-35-15-13-33-25-41-37-11-1-3-19-45(37,39(33)27-35)21-23-47(41)29-31-7-5-8-31)17-18-44(50)52-36-16-14-34-26-42-38-12-2-4-20-46(38,40(34)28-36)22-24-48(42)30-32-9-6-10-32/h13-16,27-28,31-32,37-38,41-42H,1-12,17-26,29-30H2/t37?,38?,41-,42-,45-,46-/m1/s1
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| InChIKey |
XZOSATCOBKLHCF-JNDXSTKLSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [527951] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [527951] | ||
| Delta-type opioid receptor | Target Info | Inhibitor | [527951] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||