Drug Information

Drug General Information
Drug ID
D06FNT
Former ID
DNC006770
Drug Name
VUF-8504
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467991]
Formula
C21H16N4O2
InChI
InChI=1S/C21H16N4O2/c1-27-15-11-9-14(10-12-15)21(26)25-19-16-6-2-3-7-17(16)23-20(24-19)18-8-4-5-13-22-18/h2-13H,1H3,(H,23,24,25,26)
InChIKey
TTYULORVZLXLQA-UHFFFAOYSA-N
PubChem Compound ID
10832101
PubChem Substance ID
15873383, 23089784, 42012362, 79969621, 103363161, 103961649, 135651315
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Inhibitor [528290]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 467991(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 475).
Ref 528290J Med Chem. 2006 Jul 13;49(14):4085-97.Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.