Drug Information

Drug General Information
Drug ID
D06HCP
Former ID
DNC013016
Drug Name
MELARSOPROL
Drug Type
Small molecular drug
Indication Trypanosomiasis [ICD9: 086.5-086; ICD10:B56-B57] Approved [551871]
Formula
C12H15AsN6OS2
Canonical SMILES
C1C(S[As](S1)C2=CC=C(C=C2)NC3=NC(=NC(=N3)N)N)CO
InChI
1S/C12H15AsN6OS2/c14-10-17-11(15)19-12(18-10)16-8-3-1-7(2-4-8)13-21-6-9(5-20)22-13/h1-4,9,20H,5-6H2,(H5,14,15,16,17,18,19)
InChIKey
JCYZMTMYPZHVBF-UHFFFAOYSA-N
CAS Number
CAS 494-79-1
PubChem Compound ID
10311
SuperDrug ATC ID
P01CD01
Target and Pathway
Target(s) Cysteine protease Target Info Inhibitor [530346]
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 530346J Med Chem. 2009 Sep 24;52(18):5662-72.On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.