Drug Information

Drug General Information
Drug ID
D06LNL
Former ID
DNC011943
Drug Name
Iodyl-benzene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525449]
Formula
C6H5IO2
Canonical SMILES
C1=CC=C(C=C1)I(=O)=O
InChI
1S/C6H5IO2/c8-7(9)6-4-2-1-3-5-6/h1-5H
InChIKey
BDOLQESNFGCNSC-UHFFFAOYSA-N
PubChem Compound ID
101840
Target and Pathway
Target(s) mRNA of Protein tyrosine phosphatase-1B Target Info Inhibitor [525449]
KEGG Pathway Adherens junction
Insulin signaling pathway
NetPath Pathway FSH Signaling Pathway
PANTHER Pathway Cadherin signaling pathway
Pathway Interaction Database Insulin Pathway
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Signaling events mediated by PTP1B
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Signaling events mediated by TCPTP
IGF1 pathway
EGF receptor (ErbB1) signaling pathway
Posttranslational regulation of adherens junction stability and dissassembly
PDGFR-beta signaling pathway
N-cadherin signaling events
Reactome Integrin alphaIIb beta3 signaling
Regulation of IFNG signaling
Regulation of IFNA signaling
Growth hormone receptor signaling
WikiPathways Insulin Signaling
Growth hormone receptor signaling
Leptin signaling pathway
Interferon gamma signaling
Interferon alpha/beta signaling
Integrin alphaIIb beta3 signaling
References
Ref 525449Bioorg Med Chem Lett. 1999 Feb 8;9(3):353-6.Periodinates: a new class of protein tyrosine phosphatase inhibitors.
Ref 525449Bioorg Med Chem Lett. 1999 Feb 8;9(3):353-6.Periodinates: a new class of protein tyrosine phosphatase inhibitors.