Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06SZI
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| Former ID |
DNC007681
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| Drug Name |
MCL-457
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528787] | ||
| Formula |
C21H26N2O2
|
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| Canonical SMILES |
C1CCC23CCN(C(C2C1)CC4=CC5=C(C=C34)OC(=O)N5)CC6CC6
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| InChI |
1S/C21H26N2O2/c24-20-22-17-9-14-10-18-15-3-1-2-6-21(15,16(14)11-19(17)25-20)7-8-23(18)12-13-4-5-13/h9,11,13,15,18H,1-8,10,12H2,(H,22,24)/t15-,18+,21+/m0/s1
|
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| InChIKey |
QLWCMBZVQJGYTM-RRMPHLOHSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [528787] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||