Drug General Information
Drug ID
D07QIT
Former ID
DIB003571
Drug Name
GPX-150D
Synonyms
CNDO-101; CNDO-101); GPX-150; Doxorubicin analog (cancer), Coronado; 5-imino-13-deoxy-doxorubicin
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Phase 2 [524956]
Company
Gem Pharmaceuticals LLC
Canonical SMILES
c12c([C@H](C[C@@](C2)(CCO)O)O[C@H]2C[C@@H]([C@@H]([C@@H<br />](O2)C)O)N)c(c2c(c1O)C(=O)c1c(C2=N)c(ccc1)OC)O
CAS Number
CAS 236095-26-4
Target and Pathway
Target(s) DNA topoisomerase II Target Info Modulator
References
Ref 524956ClinicalTrials.gov (NCT02267083) Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma. U.S. National Institutes of Health.