Drug Information

Drug General Information
Drug ID
D07YSJ
Former ID
DNC014557
Drug Name
(3-Amino-1-ethyl-propyl)-methyl-phosphinic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533678]
Formula
C6H16NO2P
Canonical SMILES
CCC(CCN)P(=O)(C)O
InChI
1S/C6H16NO2P/c1-3-6(4-5-7)10(2,8)9/h6H,3-5,7H2,1-2H3,(H,8,9)
InChIKey
CCGFQGUALPHBIC-UHFFFAOYSA-N
PubChem Compound ID
10103488
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [533678]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.