Drug Information

Drug General Information
Drug ID
D08FKH
Former ID
DIB014322
Drug Name
KLH-2109
Indication Endometriosis [ICD9: 617; ICD10:N80] Phase 2 [523797]
Company
Kissei Pharmaceutical Co Ltd
Target and Pathway
Target(s) Gonadotropin-releasing hormone receptor Target Info Agonist [550310]
KEGG Pathway Neuroactive ligand-receptor interaction
GnRH signaling pathway
NetPath Pathway IL1 Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Hormone ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 523797ClinicalTrials.gov (NCT01533532) A Randomized, Placebo-controlled, Double-blind Study of KLH-2109 in Patients With Endometriosis (2). U.S. National Institutes of Health.
Ref 550310Clinical pipeline report, company report or official report of Avarx.