Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08VHG
|
||||
| Former ID |
DIB002699
|
||||
| Drug Name |
RPL-554
|
||||
| Synonyms |
RPL-565; VMX-554; VMX-565; PDE 3/PDE 4 inhibitors, Kings College; PDE3/4 inhibitors (respiratory therapeutics), Rhinopharma; PDE3/4 inhibitors (nasal, respiratory disease), Verona Pharma; Trequinsin analogs (respiratory therapeutics), Kings College/Vernalis/Rhinopharma
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] | Phase 2 | [525173] | ||
| Company |
King's College London
|
||||
| Formula |
C26H31N5O4
|
||||
| Canonical SMILES |
n1(c(=O)n2c(c/c/1=N\c1c(cc(cc1C)C)C)c1c(cc(c(c1)OC)OC)C<br />C2)CCNC(=O)N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Phosphodiesterase (PDE) 3 | Target Info | Modulator | ||
| References | |||||