Drug Information

Drug General Information
Drug ID
D09KKF
Former ID
DNC002791
Drug Name
2-Amino-5-Hydroxy-Benzimidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C7H7N3O
Canonical SMILES
C1=CC2=NC(NC2=CC1=O)N
InChI
1S/C7H7N3O/c8-7-9-5-2-1-4(11)3-6(5)10-7/h1-3,7,10H,8H2
InChIKey
ZXXRHVCYZYWAHI-UHFFFAOYSA-N
PubChem Compound ID
6323183
PubChem Substance ID
7885044, 42972577, 50504433, 114480910
Target and Pathway
Target(s) Urokinase-type plasminogen activator Target Info Inhibitor [551393]
KEGG Pathway NF-kappa B signaling pathway
Complement and coagulation cascades
Transcriptional misregulation in cancer
Proteoglycans in cancer
MicroRNAs in cancer
NetPath Pathway IL2 Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Blood coagulation
Plasminogen activating cascade
CCKR signaling map ST
Pathway Interaction Database Beta1 integrin cell surface interactions
E2F transcription factor network
Beta3 integrin cell surface interactions
Osteopontin-mediated events
Validated transcriptional targets of AP1 family members Fra1 and Fra2
amb2 Integrin signaling
ATF-2 transcription factor network
AP-1 transcription factor network
Beta2 integrin cell surface interactions
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
FGF signaling pathway
Reactome Dissolution of Fibrin Clot
WikiPathways DNA Damage Response (only ATM dependent)
Senescence and Autophagy in Cancer
Complement and Coagulation Cascades
Endochondral Ossification
Wnt Signaling Pathway
Wnt Signaling Pathway and Pluripotency
Blood Clotting Cascade
Dissolution of Fibrin Clot
Osteopontin Signaling
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.