Drug Information

Drug General Information
Drug ID
D0A3CL
Former ID
DIB001791
Drug Name
AZD1979
Indication Obesity [ICD9: 278; ICD10:E66] Phase 1 [524658]
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Modulator [550345]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 524658ClinicalTrials.gov (NCT02072993) A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males. U.S. National Institutes of Health.
Ref 550345Phase I clinical trial of AZD1979 for treating obesity. AstraZeneca plc