Drug Information

Drug General Information
Drug ID
D0A9PS
Former ID
DNC000210
Drug Name
Anandamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539503]
Formula
C22H37NO2
InChI
InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
InChIKey
LGEQQWMQCRIYKG-DOFZRALJSA-N
CAS Number
CAS 94421-68-8
PubChem Compound ID
5281969
PubChem Substance ID
13860, 841250, 4266218, 7978708, 8616858, 10587964, 11534104, 12014921, 14900691, 24890438, 26754689, 26754690, 26754691, 26754692, 26758228, 39315536, 47588771, 47736226, 47885183, 49681166, 49846802, 49964830, 50091575, 50110763, 53788936, 56365469, 57358469, 57389789, 71821418, 76140856, 81054506, 85208952, 85788018, 91702793, 92309949, 99300862, 99302381, 103178779, 104046462, 113856279, 124976956, 126524997, 127331025, 127331026, 127331027, 134339707, 135061638, 135651438, 137002864, 140063420
ChEBI ID
ChEBI:2700
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Agonist [537577]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539503(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2364).
Ref 537577Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. Life Sci. 2009 Jul 1.