Drug Information

Drug General Information
Drug ID
D0DY1C
Former ID
DNC012642
Drug Name
9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533959]
Formula
C11H19NO3S
Canonical SMILES
C1CCCC(NC(=O)C(CC1)CS)C(=O)O
InChI
1S/C11H19NO3S/c13-10-8(7-16)5-3-1-2-4-6-9(12-10)11(14)15/h8-9,16H,1-7H2,(H,12,13)(H,14,15)
InChIKey
MWNHNWDDMZYRSH-UHFFFAOYSA-N
PubChem Compound ID
19930853
Target and Pathway
Target(s) Neutral endopeptidase Target Info Inhibitor [533959]
KEGG Pathway Renin-angiotensin system
Hematopoietic cell lineage
Protein digestion and absorption
Alzheimer's disease
NetPath Pathway EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Primary Focal Segmental Glomerulosclerosis FSGS
Alzheimers Disease
References
Ref 533959J Med Chem. 1993 Nov 26;36(24):3821-8.Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.
Ref 533959J Med Chem. 1993 Nov 26;36(24):3821-8.Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.