Drug General Information
Drug ID
D0E1YT
Former ID
DNC009885
Drug Name
ISOMER A
Indication Discovery agent Investigative [530247]
Target and Pathway
Target(s) Calcitoningene-related peptide type 1 receptor Target Info Inhibitor [530247]
KEGG Pathway Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Reactome G alpha (s) signalling events
Calcitonin-like ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Endothelin Pathways
GPCR ligand binding
GPCR downstream signaling
References
Ref 530247Bioorg Med Chem Lett. 2009 Aug 15;19(16):4740-2. Epub 2009 Jun 17.The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
Ref 530247Bioorg Med Chem Lett. 2009 Aug 15;19(16):4740-2. Epub 2009 Jun 17.The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.