Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0E6GH
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| Former ID |
DNC009670
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| Drug Name |
14-O-phenylpropylnaltrexone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529991] | ||
| Formula |
C29H33NO4
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| Canonical SMILES |
C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)O)O5)OCCCC7=<br />CC=CC=C7
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| InChI |
1S/C29H33NO4/c31-22-11-10-21-17-24-29(33-16-4-7-19-5-2-1-3-6-19)13-12-23(32)27-28(29,25(21)26(22)34-27)14-15-30(24)18-20-8-9-20/h1-3,5-6,10-11,20,24,27,31H,4,7-9,12-18H2/t24-,27+,28+,29-/m1/s1
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| InChIKey |
KOXWKZKLXNZQAO-ZLPBPMGLSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [529991] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [529991] | ||
| Kappa-type opioid receptor | Target Info | Inhibitor | [529991] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||