Drug Information

Drug General Information
Drug ID
D0EE6L
Former ID
DNC005570
Drug Name
BP-897
Drug Type
Small molecular drug
Indication Cocaine addiction [ICD9: 304.2; ICD10:F14.2] Discontinued in Phase 2 [542612], [547037]
Formula
C26H31N3O2
InChI
InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30)
InChIKey
MNHDKMDLOJSCGN-UHFFFAOYSA-N
PubChem Compound ID
3038495
PubChem Substance ID
11110867, 11110868, 11466587, 11467707, 11486294, 11564242, 14782328, 17404728, 24278279, 36106208, 47349351, 48018895, 48094533, 48243353, 48393921, 49698551, 50105904, 50105905, 53777271, 53790769, 57353732, 79551160, 85208979, 85230943, 85788982, 90340615, 92303556, 103194907, 103856467, 104012598, 111646208, 121360835, 124749503, 124879457, 128620357, 134342775, 140156791, 144240233, 144240235, 162220559, 163564119, 172649623, 198955573, 223365960, 228262829
Target and Pathway
Target(s) D(3) dopamine receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapse
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, Other
References
Ref 542612(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7625).
Ref 547037Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012397)